Cajun Chicken Broccoli Alfredo

Featured in: Center of the plate recipes

Succulent chicken breast bites are seasoned with Cajun spices, then sautéed to golden perfection and paired with vibrant broccoli. The dish is enveloped in a rich, melting cheese Alfredo sauce, with penne pasta providing a hearty base. Each bite balances mild heat, creamy smoothness, and fresh green broccoli. Finished in one pan, it's a quick, comforting pasta packed with bold flavors perfect for weeknight dinners or a special treat.

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Updated on Wed, 29 Oct 2025 12:44:59 GMT
A delicious Cajun Chicken Broccoli Alfredo dish served in a silver bowl. Pin it
A delicious Cajun Chicken Broccoli Alfredo dish served in a silver bowl. | myhomemaderecipe.com

There is something magical about Cajun Chicken Broccoli Alfredo when you crave a creamy pasta dinner with a little heat This recipe draws bold flavor from Cajun spices while tender chicken and crisp broccoli create a hearty bite The first time I put this together was after a long week night craving comfort food with a twist Since then it has become a favorite for when we need something quick yet special

My whole family loves this dish especially because it offers both the richness of Alfredo and the punchy pop of Cajun I often make it as a weeknight treat and it always feels restaurant worthy

Ingredients

  • Chicken breast: Look for fresh firm fillets as they cook up tender and juicy
  • Salt and black pepper: Classic seasonings that let the Cajun spice stand out
  • Butter: Adds richness and blends perfectly with olive oil for sautéing
  • Olive oil: Helps the chicken brown for even flavor distribution
  • Garlic: Mince fresh cloves for the best aroma and depth
  • Heavy cream: Opt for 35 percent cream to create a truly luscious Alfredo texture
  • Milk: Balances out the heaviness of cream without sacrificing silkiness
  • Mozzarella or Monterey Jack cheese: Choose the freshest block cheese and grate it yourself for smooth melting
  • Broccoli florets: Pick bright green heads without yellowing or limp spots for crisp freshness
  • Pasta: Penne holds sauce beautifully but any shape you love works
  • Cajun seasoning: Use your favorite blend or make your own with smoked paprika cayenne garlic powder and oregano You can control the spice level

Instructions

Season the Chicken:
Sprinkle chicken breast pieces generously with salt black pepper and Cajun seasoning Rub well to coat and let it rest for several minutes allowing the spices to absorb for deeper flavor
Cook the Pasta:
Bring a large pot of salted water to a rolling boil Add your choice of pasta and cook until just al dente so it remains slightly firm Drain well and set aside while you prep the rest of the dish
Prepare the Broccoli:
While the pasta cooks steam or blanch the broccoli florets until they turn a vivid green and are fork tender but not mushy Chill briefly under cold water to preserve color and texture
Cook the Chicken:
Heat butter and olive oil together in a heavy skillet or roomy pot over medium-high Once sizzling add chicken in a single layer Sauté for about five minutes without stirring too much This develops a golden crust Turn pieces and finish cooking until no longer pink throughout Lift chicken onto a plate and keep warm
Start the Sauce:
Lower the heat to medium Pour the minced garlic into the same pot Stir gently until fragrant watching carefully so it does not burn Pour in heavy cream and then milk whisking continuously to keep things silky and prevent sticking Watch for small bubbles along the edge without letting it boil
Melt the Cheese:
Once the sauce is gently simmering add the grated mozzarella or Monterey Jack cheese A handful at a time works best Stir after each addition until fully melted and the sauce looks smooth
Combine Everything:
Return the cooked pasta chicken and broccoli to the pot Stir well to coat everything with the cheesy Cajun cream sauce Simmer for a couple of minutes just until everything is piping hot Taste and adjust the seasoning now
Serve:
Dish up the Cajun Chicken Broccoli Alfredo while it is steaming and saucy Top with extra cheese cracked black pepper or a sprinkle of fresh parsley for more color
A delicious meal of chicken and broccoli in a bowl. Pin it
A delicious meal of chicken and broccoli in a bowl. | myhomemaderecipe.com

Broccoli is my secret hero ingredient here It soaks up the Cajun cream and adds a fresh pop Every time we make this dish my daughter insists on extra broccoli because she loves the way it tastes in the sauce

Storage Tips

Store leftovers in a sealed container in the fridge for up to three days To reheat add a splash of milk before microwaving or warming on the stovetop This brings the sauce back to life and keeps things from drying out

Ingredient Substitutions

You can use boneless chicken thighs if you like darker meat or even shrimp for a seafood twist Monterey Jack or mozzarella both work well but cheddar gives a stronger flavor Gluten-free pasta is a good alternative if anyone at your table is sensitive

Serving Suggestions

Serve this Alfredo with a crisp green salad and some crunchy garlic bread for a fuller meal It also pairs nicely with a glass of dry white wine or sparkling water with lemon

Cultural Context

Alfredo sauce is Italian in origin but Cajun seasoning gives this dish a kick typical of Louisiana cooking It is the blend of Italian creamy comfort and Southern heat that makes this pasta recipe stand out on the table and in memories

A delicious meal of chicken and broccoli in a silver bowl. Pin it
A delicious meal of chicken and broccoli in a silver bowl. | myhomemaderecipe.com

This cozy Cajun Chicken Broccoli Alfredo comes together with easy steps for maximum flavor With each bite it offers creamy comfort and just the right kick

Frequently Asked Questions

→ How spicy is the Cajun seasoning?

The heat level depends on the Cajun blend used and how much you add. Start with 1 teaspoon and customize to taste.

→ Can I use frozen broccoli?

Yes, frozen broccoli works well—just steam or cook it until bright green and tender before adding.

→ What type of cheese is best?

Mozzarella or Monterey Jack cheese melts smoothly, but you can substitute with your favorite melty cheese.

→ Can this dish be made ahead?

While best served fresh, you can store leftovers in the fridge for up to two days and reheat gently on the stove.

→ What pasta shapes work well?

Penne is classic, but rotini, fusilli, or farfalle are all excellent at holding the creamy sauce.

→ How do I prevent the sauce from curdling?

Keep the heat medium and add the milk/cream gradually while stirring constantly for a smooth sauce.

Cajun Chicken Broccoli Alfredo

Cajun-spiced chicken and broccoli blend in creamy Alfredo sauce with pasta for a satisfying meal.

Prep Time
20 Minutes
Cook Time
25 Minutes
Total Time
45 Minutes
By: Susan

Category: Main Dishes

Difficulty: Intermediate

Cuisine: Cajun-inspired

Yield: 4 Servings (Serves 4 portions)

Dietary: ~

Ingredients

→ Protein

01 680 g boneless, skinless chicken breast, cut into bite-sized pieces

→ Seasonings

02 Fine sea salt, to taste
03 Freshly ground black pepper, to taste
04 Cajun seasoning, 2–3 g or to taste

→ Fats

05 15 ml unsalted butter
06 15 ml olive oil

→ Aromatics

07 4 garlic cloves, minced

→ Sauce Base

08 240 ml heavy cream (35% fat)
09 240 ml whole milk

→ Cheese

10 140 g grated mozzarella or Monterey Jack cheese

→ Vegetables

11 100 g broccoli florets, fresh or lightly steamed

→ Pasta

12 100 g penne pasta

Instructions

Step 01

Toss the chicken pieces with salt, black pepper, and Cajun seasoning. Allow to stand for several minutes to promote seasoning adherence.

Step 02

Cook penne in generously salted boiling water until al dente, following package instructions. Simultaneously, steam or blanch broccoli florets until vibrant and just tender. Drain and set both aside.

Step 03

Heat butter and olive oil in a large sauté pan over medium-high heat. Add seasoned chicken and sear, cooking approximately 5 minutes per side, until golden brown and cooked through. Remove chicken and reserve.

Step 04

Reduce the heat to medium. In the same pan, add minced garlic and sweat for 30 to 60 seconds, stirring until aromatic but not browned. Pour in heavy cream and gradually add milk, stirring constantly. Bring to a gentle simmer.

Step 05

While the sauce is hot but not boiling, stir in grated mozzarella or Monterey Jack, mixing until completely melted and the sauce achieves a silky consistency.

Step 06

Add cooked penne, sautéed chicken, and prepared broccoli to the sauce. Stir together thoroughly to coat all elements evenly, heating gently so the mixture is fully warmed.

Step 07

Taste and correct seasoning with additional salt, pepper, or Cajun spice as needed. Serve immediately, garnishing with extra cheese, cracked pepper, or fresh parsley if desired.

Notes

  1. For optimal texture, do not overcook the broccoli; it should retain a slight bite and vibrant color.
  2. Allowing the chicken to rest after searing preserves its juiciness when incorporated into the sauce.

Tools You'll Need

  • Large sauté pan or skillet
  • Medium saucepan
  • Colander
  • Knife and chopping board

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains milk and cheese (dairy)
  • Contains wheat (gluten)

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 635
  • Total Fat: 34.5 g
  • Total Carbohydrate: 38.2 g
  • Protein: 45.1 g